Continuous production of penicillin in a fluidized-bed bioreactor.
نویسندگان
چکیده
منابع مشابه
Penicillin Production in an Inverse Fluidized Bed Bioreactor
The inverse fluidized bed bioreactor was adapted for the axenic culture of heterotrophic microorganisms. Penicillin V synthesized by Penicillium chrysogenum ATCC 28089 was used as a model system for secondary metabolite production. The biomass growth rate was controlled by the rate of nutrient addition while an eroder in the inner draft tube limited the maximum biofilm thickness. When a lactose...
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The fermentation kinetics of penicillin production by Penicillium chrysogenum was carried out at 27°C and pH 6.0. Batch and repeated batch fermentations using agar-immobilized cells in fluidized bed bioreactor were studied for their potential application in production of penicillin from lactose, a fermentable sugar. Kinetics of immobilized cell fermentation, showed the penicillin yield of ~0.01...
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A fluidized bed bioreactor has been used to carry out biological denitrification in the present work as it offers many advantages over other types of reactors. Plastic beads of low density (1055 kg/m3) were used as fluidizing media with Pseudomonas stuzeri, a denitrifying microorganism immobilized on them. The denitrification rate under different operating conditions was studied. The results of...
متن کاملFructose Production by Inulinase Covalently Immobilized on Sepabeads in Batch and Fluidized Bed Bioreactor
The present work is an experimental study of the performance of a recently designed immobilized enzyme: inulinase from Aspergillus sp. covalently immobilized on Sepabeads. The aim of the work is to test the new biocatalyst in conditions of industrial interest and to assess the feasibility of the process in a fluidized bed bioreactor (FBBR). The catalyst was first tested in a batch reactor at st...
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ژورنال
عنوان ژورنال: JOURNAL OF CHEMICAL ENGINEERING OF JAPAN
سال: 1990
ISSN: 0021-9592,1881-1299
DOI: 10.1252/jcej.23.505